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The 10 years (1980-1989) experience of 43 patients with chronic pancreatitis at Seoul National University Hospital has been analysed to investigate the relationship between history of pain, morphologic change of pancreas (calcification), and diabetes mellitus (DM), and to study indications of surgery and complications. The main etiologic factor was probably alcohol (30 case). The mean age of the patients with alcohol-induced chronic pancreatitis was 9 years below that of the other patients in men (no statistic difference). Calcifications were found in 29 patients, DM patients to require insulin therapy were 13 patients. calcifications were found in 12 patients among 13 diabetes mellitus patients (p<0.05). Pancreatic duct abnormality was found in 29 patients [moderate change of main pancreatic duct dilatation and/or stenosis; 22 cases, severe change of the above findings; 7 cases, filling defect (probably pancreatic duct stone); 7 cases.] Twenty-five patients had been lost average 10.5 Kg/3 months body weight, among whom 11 DM patients were included. There was no relationship between history of pain, morphologic change, and diabetes mellitus. The complications of chronic pancreatitis in 43 patients were pseudocyst (5 cases), comrnon bile duct stenosis (3 cases), splenic vein thrombosis (2 cases). The indications for surgery were pseudocyst (2 cases), cholestatic jaundice (1 case), GI bleeding due to splenic vein thrombosis and portal vein thrombosis (2 cases), pain relief (5 cases) and differential diagnosis from cancer (2 cases). There was no operative mortality.
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